Emergency teams were mobilised to Godshill Road between Shanklin and Whitely Bank at just before 23:20 following reports of a road traffic collision, as first reported by Island Echo.
Upon arrival of the first Police, fire and ambulance crews it was established that the driver of the small hatchback had been thrown from the vehicle. The Mini was found on its side in a field around 20 metres off the road having hit and Bank and rolled.
No other vehicles are thought to have been involved in the incident, which resulted in the road being closed for over 6 hours. It re-opened at around 06:00 this morning.
The 25-year-old male casualty from Newport is said to be in a stable condition. He is being treated for neck, shoulder and facial injuries.
Hampshire Constabulary are continuing to investigate the circumstances of the crash and are asking for any witnesses Tom come forward by calling 101.