5 Police vehicles and 2 ambulances are on scene at the junction with Red Road.
All traffic is currently being diverted in the area via St Edmunds walk.
UPDATE @ 19:50 – The main road connecting Ryde and Newport has now re-opened in both directions, although there are delays.
The motorcyclist is not thought to have sustained any serious injuries. They are currently being checked over by paramedics from the Isle of Wight Ambulance Service and are expected to be conveyed to St Mary’s Hospital.
UPDATE @ 20:40 – It has been confirmed that the motorcyclist suffered a medical episode whilst riding.
Emergency services have now stood down from the incident. The scene has been cleared.