A Vauxhall Zafira has come to a stop into a field after leaving the carriageway at Marshcombe Shute, between Yarbridge and Yaverland.
Emergency services were alerted to the crash at around 15:55, with fire appliances from Ryde and Shanklin mobilised for scene safety.
Island Echo is told that no other vehicles have been involved in the incident, which occurred on a downhill section. It is understood the Zafira driver was overtaking a tractor at the time of the crash.
An ambulance from the Isle of Wight Ambulance Service is in attendance at the scene alongside Police.
The 4 occupants of the vehicle are being checked over by paramedics.