Firefighters from Newport and Cowes are on scene at the main entrance to the lower ground floor of the hospital, which is situated off Parkhurst Road.
Those at the scene say that part of the hospital has been evacuated as investigations are carried out. The situation appears to be under control, Island Echo is told.
The Isle of Wight Fire and Rescue Service was called out shortly before 18:20 with 3 appliances and an aerial ladder platform mobilised.
UPDATE @ 21:20 – It has been confirmed that the smell of burning in the scanning department prompted the call out. However, following investigations, the alert has been deemed a false alarm.
Fire crews have now stood down and returned to station.