Emergency services are currently in attendance on Mitchell Avenue in the town having been alerted to the incident at just before 14:25.
The road is closed in both directions with a Police cordon established to preserve the scene.
The motorcycle involved had been removed from the scene by the time Police arrived, but the incident isn’t being treated as a hit and run. The motorcycle and it’s rider have now been located.
Motorists and local buses are being diverted.
The casualty – a male pedestrian – is being tended to by air ambulance doctors at the helicopter landing site at Ventnor Rugby Club. He has been taken to the landing site by the Isle of Wight Ambulance Service.
Island Echo understands the male is being treated for what is thought to be a serious leg injury.
UPDATE @ 15:35 – Ventnor Coastguard Rescue Team have aided with gaining access to the padlocked gate at Ventnor Rugby Club, allowing the casualty to be transferred to the air ambulance for onward conveyance.
UPDATE @ 16:10 – Police have confirmed that the pedestrian has suffered serious but not life-threatening injuries.
The air ambulance has in the last few minutes taken off from the rugby club and is flying the casualty directly to Southampton General Hospital.
The road has now re-opened in both directions.