Emergency services are currently dealing with a RTC at Limerstone on the outskirts of Shorwell.
It is understood that fire, police and ambulance crews are all in attendance. The main road between Shorwell roundabout and Brighstone has been closed.
The 999 call came in shortly before 18:20 this evening.
It is not known how serious the collision is or how many people or vehicles are involved.
UPDATE: Fire crews from Newport have since left the scene and have returned to station.
UPDATE @ 20:38: Three vehicles were believed to be involved in the collision tonight including a Volkswagen Golf GTI and a Land Rover Defender. The road is now clear.