Police were called to Knighton Shute shortly before 18:50 following reports of a vehicle on its roof on the rural road, which runs between The Downs and Newchurch.
Island Echo understands the occupant or occupants of the vehicle ran from the scene, prompting an aerial search by the National Police Air Support helicopter.
Members of the public came across the wreckage of the small hatchback having passed two persons walking away from the scene in an erratic manner, refusing assistance.
The road remains closed in both directions whilst the car is recovered and debris is cleared.
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