Emergency services were called to the scene on Whitwell Road near to Southford Lane shortly before 11:15.
Island Echo understands a Calor Gas lorry has collided with a Ford Fiesta.
No one has been injured in the incident, which has resulted in the large lorry coming to rest in a hedge lining the carriageway.
Police have closed the road between Southford Lane and Sheepwash Lane whilst recovery of both vehicles is carried out.
UPDATE @ 12:45 – The road has now reopened in both directions