The incident has occurred on the S-bend of the A3020 between Blackwater and Rookley and has resulted in the road becoming blocked in both directions.
Emergency services were called to the scene shortly before 19:20.
UPDATE @ 19:52 – The occupants of the red Ford Focus are understood to have escaped any serious injury.
The road has been closed by Police at the junction with Highwood Lane, Rookley.
The recovery of the vehicle has been arranged.
UPDATE @ 20:05 – Route 3 buses are diverting via Merstone until further notice, according to Southern Vectis.
UPDATE @ 20:09 – Blackwater Hollow has reopened in both directions, with Southern Vectis Route 3 buses resuming a normal service.